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While this treatment approach is sufficient to correct for peripheral symptoms such as anemia, the accompanying neurological defects are not easily addressed since patients require supraphysiological folate concentrations in blood to be able to increase CSF folate

For ongoing benefits, regular sessions typically every two to three weeks are recommended

Yap, E.H

7,1922 Many of these medications require dosing adjustment in older patients and in those with reduced creatinine clearance

NNMT inhibition could have effects on methylation balance and other metabolic pathways that have not been evaluated in people

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